Anaesthetic management during open and percutaneous irreversible electroporation

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Reply from the authors. Anaesthetic management during open and percutaneous irreversible electroporation.

BACKGROUND Irreversible electroporation (IRE) is a novel tumour ablation technique involving repetitive application of electrical energy around a tumour. The use of pulsed electrical gradients carries a risk of cardiac arrhythmias, severe muscle contractions, and seizures. We aimed to identify IRE-related risks and the appropriate precautions for anaesthetic management. METHODS All patients w...

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Temperature considerations during irreversible electroporation

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Finite Element Analysis of Tissue Conductivity during High-frequency and Low-voltage Irreversible Electroporation

Introduction: Irreversible electroporation (IRE) is a process in which the membrane of the cancer cells are irreversibly damaged with the use of high-intensity electric pulses, which in turn leads to cell death. The IRE is a non-thermal way to ablate the cancer cells. This process relies on the distribution of the electric field, which affects the pulse amplitude, width, and electrical conducti...

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Percutaneous ablation of peribiliary tumors with irreversible electroporation.

PURPOSE To assess biliary complications after irreversible electroporation (IRE) ablation of hepatic tumors located < 1 cm from major bile ducts. MATERIALS AND METHODS A retrospective review was conducted of all percutaneous IRE ablations of hepatic tumors within 1 cm of the common, left, or right hepatic ducts at a single institution from January 2011 to September 2012. Computed tomography i...

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Tissue heating during tumor ablation with irreversible electroporation

Exposing biological cells to sufficiently strong external electric fields causes electroporation of cell membranes, i.e. occurrence of transient or permanent permeable pathways between the interior and exterior of the cell. Electroporation can be used to introduce various molecules into cells (reversible electroporation) or to kill cells (irreversible electroporation), which can in turn be used...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 2014

ISSN: 0007-0912

DOI: 10.1093/bja/aeu256